Friday, 26 September 2014

A Microfluidic Flow Chemistry Platform for Organic Synthesis: the Hofmann Rearrangement

A. Palmieri, S.V. Ley, K. Hammond, A. Polyzos and I.R. Baxendale, Tetrahedron Lett200950, 3287-3289.
We report on the use of commercially available chemical microreactors to effect the Hofmann rearrangement of aromatic amides to the corresponding carbamates.

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